19/03/2019

作文代写:纳米医学

墨尔本论文代写

作文代写:纳米医学

纳米医学已显示出很大的发展潜力。有几个因素表明纳米药物具有巨大的治疗效果。然而,一些因素阻碍了纳米药物在主流药物领域的发展。常见的主要因素是血脑屏障(BBB)和细胞毒性。这些都是详细的探索。下面将详细解释这些因素。BBB被认为是纳米医学中最重要的。它主要由半透膜组成。血脑屏障的基本功能是将血液从脑脊液中分离出来。它是身体为防止有害物质进入大脑而提供的自然防御机制。本质上由微血管内皮细胞、基底膜、周细胞、星形胶质细胞和神经元[4]组成。星形细胞足突是血脑屏障高不透水性的原因。它起着阻挡大分子进入的作用。星形细胞足突超越血脑屏障。这些是在血脑屏障中发现的紧密连接的原因。它不允许粒子轻易进入大脑。与身体的内皮细胞相比,它有两个不同之处。在这个BBB中有连续的紧密连接位点。在这些星形胶质细胞中,Occludin和Claudin-5蛋白含量丰富。研究表明,这些蛋白是星形胶质细胞形成紧密连接[6]的根本原因。

作文代写:纳米医学
大脑毛细血管中的这些紧密连接阻止了分子的扩散。除此之外,在血脑屏障中没有发现细胞内的小泡。这与在身体其他部位发现的内皮细胞明显不同。了解血脑屏障的功能结构及其组成对有效地给药具有重要意义。BBB有很多好处,但它也阻碍了用于治疗癌症的药物的进展。BBB已被证明是阻碍癌症药物在体内传递的主要原因。BBB具有选择性渗透率。它只允许特定的粒子来确保大脑[6]的正常运作。由于这个因素,它确实允许某些必需的氨基酸和葡萄糖从血液中运输到大脑。重要的氨基酸不能在大脑中合成。在脑[7]中发现的必需氨基酸具有广泛的整体功能。水也通过血脑屏障中的特定通道输送。因此BBB是一把双刃剑。它在保护大脑的同时也阻碍了纳米医学的发展。血脑屏障是机体为防止病原体进入机体而产生的先天潜能。BBB确保人类自然地免受疾病的侵害。因此,它只允许某些粒子进入身体。这阻碍了纳米颗粒作为治疗和药物标记物的应用。

作文代写:纳米医学

Nanomedicine has shown a lot of potential for development. There are several factors that show that nanomedicine has immense therapeutic effects. Yet some factors impede the progress of the nanomedicines in mainstream medication. Main factors that are found to be common are the Blood Brain Barrier (BBB) and cytotoxity. These are explored in detail. These factors are explained in detail in the following. BBB is considered to be of paramount importance in nanomedicines. It primarily comprises of a semi-permeable membrane. Fundamental function of this blood brain barrier is separate blood from the cerebrospinal fluid. It is the natural defense mechanism provided by the body to prevent harmful substances from entering the brain. Essentially, it comprises of micro vascular endothelium, basement membrane, pericytes, astrocytes and neurons [4]. Astrocytic foot process is the reason for the high levels of impermeability of the BBB. It serves as a barricade where large molecules are not allowed to enter. Astrocytic foot processes surmounts the BBB. These are the reasons for the tight junctions that are found in the BBB. It does not allow particles to enter into the brain easily [4]. It differs in two ways when compared to endothelial cells of the body. There are continuous sites of tight junctions that are found in this BBB. Occludin and Claudin-5 proteins are found to be abundant in these astrocytes. According to research it is suggested that these proteins are the fundamental reason for astrocytes to form tight junctions [6].

作文代写:纳米医学
These tight junctions in the brain capillaries prevent diffusion of molecules. Apart from this there are no intracellular vesicles that are found in this BBB. This is markedly different from the endothelial cells that are found in other parts of the body. It is important to understand the BBB functional structure and its composition to administer drugs effectively [6]. BBB has numerous benefits but it also impedes the progress of the medicines that are administered to treat cancer. BBB has proven to be the major cause for impeding the delivery of cancer medications in the body. BBB has selective permeability. It only allows certain particles to ensure that there is smooth functioning of the brain [6]. Owing to this factor it does allow certain essential amino acids and glucose form the blood to be transported into the brain. Amino acids that are vital cannot be synthesized in the brain. There is extensive integral functionality of the essential amino acids that are found in the brain [7]. Water is also sent through specific channels in the BBB. Hence the BBB serves as a double-edged sword. It protects the brain and at the same time impedes the progress of the nanomedicine. BBB is the innate potential developed by the body to prevent pathogens to enter into the body. BBB ensures that humans are naturally protected against diseases. Owing to this, it allows only certain particles to enter into the body. This has impeded nanoparticles to serve as therapeutic and medicinal markers.

澳洲代写计算机程序设计概论

澳洲论文代写教你提高用词准确度